TRIS as flame retardant, chronic poison at home

In modern life, flame retardants are almost everywhere. Thousands of flame retardant molecules are just like the alert little guards, and they are silently guarding your life and property safety. Let us stay away from the threat of fire. However, flame retardants may become a chronic poison in our lives.


A study by Duke University in the United States shows: In order to prevent fires, some household products made of petroleum extracts, such as sofas, curtains, floor mats, car seat cushions, etc., will add flame retardant ingredients during the manufacturing process, which will hinder the development of children's nervous system and even cause cancer.

The study found that:


The amount of flame retardant contained in the dust of California residents' homes has already exceeded the safety limit. Of the 32 different dust samples, 55 different flame retardant compounds were detected. These household products with flame retardant ingredients will gradually release toxic chemicals. Especially when the furniture has a rupture, the toxic substances will be "jetted" out, dissolved in the dust or sucked into the lungs.


These harmful flame retardants are mainly two chemicals:

• One is Tris(Hydroxymethyl) Aminomethane (TRIS), a buffer solution commonly used in biological preparation and medical preparation. It is commonly used in: gel electrophoresis buffer, such as TAE or TBE; preparation of Laemmli buffer; preparing running buffer and loading buffer together With glycine and SDS; binding buffer and an eluent in anion exchange chromatography; RNA hybridization and DNA cleavage. Because of its potential health risks, it was banned for infant and young children’s clothing as early as 1977, but it was used in sofas and other household items;
• The other is pentabromodiphenyl ether. A large number of studies have shown that brominated flame retardants can infiltrate into the human environment and accumulate in living organisms over time, which can destroy endocrine activity, affect thyroid function regulation and even brain development. In particular, excessive exposure of pregnant women can directly lead to newborn baby's low birth weight, low IQ and impaired behavior. For this reason, after 2005, some US producers began to voluntarily discard this brominated flame retardant, which has been abandoned in most developed countries.

Experts in China also recommend:
For flame-retardant furniture such as sofas, curtains, and wallpapers, it is best to use a phosphorus-based flame retardant. Because bromine is highly carcinogenic, it has a greater impact on children, leading to childhood leukemia and genetic mutations.


At the same time, in order to minimize the impact of the flame retardant on the body, the dust in the home should be minimized, go to the air place, wash your hands everyday, and the electric blanket or the flame retardant mattress should not be used as much as possible.


Edited by Suzhou Yacoo Science Co., Ltd.

TRIS Buffer Tablets? Simple, fast, and easy to save

Tris(Hydroxymethyl) Aminomethane (TRIS) buffer solution is a biological reagent, which is a buffer solution commonly used in biological preparation and medical preparation. For example, it’s commonly used in peprotech recombinant cytokines and protein solubilization, and widely used as solvent for nucleic acid and proteins electrophoresis. Usually, it is used as a liquid, but it is not easy to store for a long time and the preparation is inconvenient. If it is made into a tablet, the above problem will be well solved.

Some researchers have provided a preparation method of TRIS buffer tablets which are ready to use, easy to store, simple and quick to prepare. The steps are as follows:
(1) TRIS, boric acid, EDTA, cross-linked amylose (weight ratio: 54:22~23:3.0~3.5:3.3~4), pulverized to make into particles with 100~200 mesh; The main material trishydroxymethylaminomethane is in the grade of pharmacopoeia; Excipients boric acid and EDTA are AR grade, crosslinked amylose and microcrystalline cellulose are biological grade;
(2) mixing and stirring evenly;
(3) Tablet press, pressure 2~4 tons;
(4) Weighing and testing;

(5) Packaging.

The pH of the TRIS buffer solution varies with temperature greatly, making it more difficult to formulate the solution. The buffer tablet provided by the method is simple and easy to use, and can be quickly opened and disintegrated as long as the tablet is put into the quantitative water, thereby obtaining a buffer solution with an accurate pH value, saving the user's manpower and material resources and improving work efficiency. At the same time, it is easy to store, carry and transport. The storage period is up to 3~5 years, and suitable for industrial production.

Edited by Suzhou Yacoo Science Co., Ltd.