2019年10月16日星期三

2-pyrrolidone application

2-pyrrolidone is miscible with water, alcohol, ether, chloroform, benzene, ethyl acetate and carbon disulfide; it is insoluble in petroleum ether, and its main use is as polyvinylpyrrolidone (PVP) monomer N-vinylpyrrolidone (NVP) The raw material is also a high-grade solvent, which is used in the production of pharmaceuticals, resins, acetylene recycling, and floor wax special inks. NVP can be prepared by reacting 2-pyrrolidone with acetylene and then polymerizing to obtain PVP. PVP has excellent solubility, low toxicity, film formation, complexation, surface activity and chemical stability, and is widely used in medicine, food, and day. In the fields of chemicals, coatings, polymer polymerization, etc., there are many uses in textiles, printing and dyeing, papermaking, photosensitive materials, agriculture and animal husbandry. There are three main industrial production routes for 2-pyrrolidone: 1) Rebec method: raw materials acetylene and formaldehyde are first reacted to form 1.4-butynediol, hydrogenated to 14-butanediol, converted to γ-butyrolactone, and then Ammonia is reacted to obtain 2-pyrrolidone. 2) Recently, due to the successful development of a new process for the oxidation of butane or 1.4-butanediol, the source of γ-butyrolactone is abundant, so it has become the main route for the production of pyrrolidone series products. It should be obtained as 1.4 dibutyl, partially hydrogenated to aminobutyronitrile, and hydrolyzed to 2-pyrrolidone.
2-pyrrolidone can be used as a high boiling point solvent for petroleum processing; to prepare N-vinylpyrrolidone, acrylonitrile, aminobutyric acid; also as a plasticizer for coatings; to form a polyamide under the action of benzoyl chloride and an alkali metal -4 and so on. 2-Pyrrolidone is a class of pyrrolidine compounds having a five-membered lactam ring, which is widely found in natural products and various synthetic compounds. Since pyrrolidone compounds have a wide variety of biological activities and are widely used in the field of medicine, many pyrididone structures can be modified and functionalized to prepare a plurality of compounds having various biological activities.

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